Dice Table
Dice Control Practice Craps Tables Craps dice control practice tables for tabletop use or with folding legs. We also have a separate craps end rail so you can have the real feel of a casino craps table when you practice. How do you roll the dice? This beautiful table can be rotated to show any side you choose. Available in a gloss white or red, this piece will compliment your gaming room in a big way. Measuring 16 inches square, it is the perfect size for use as an end table or foot stool. This Dice Table is made of strong and durable. TTRPG Accessories, RPG Table Top Games. Cat Shaped Dice Tray CozyGamer. From shop CozyGamer. 5 out of 5 stars (10,018) 10,018 reviews $ 18.00. Before starting Beau explained that dice setters are not able to control every single throw but only influence the dice towards certain numbers. At a 3-4-5x odds table the house edge is only 0.374% so it only takes a slight influence of the dice to overcome that house advantage. Dice Control Practice Craps Tables Craps dice control practice tables for tabletop use or with folding legs. We also have a separate craps end rail so you can have the real feel of a casino craps table when.
Objective: To investigate the effect of 5 weeks dapagliflozin 10 mg once daily treatment on glucose and lipid fluxes in patients with type 2 diabetes.
Study design: Single center single arm (mechanistic) intervention trial.
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Study Population: Male or postmenopausal female patients with type 2 diabetes BMI > 25 kg/m2and more than 12 weeks a stable dose of metformin treatment > 1500mg, HbA1C ≥6.5% - <8.5%, Fasting Plasma Glucose (FPG) <13.2 mmol/l, LDL cholesterol >2.5 mmol/l, willing to switch to rosuvastatin 10mg once daily for 4 weeks, and then receive 10 mg dapagliflozin once daily orally, for 5 weeks.
Treatment: After a statin washout fase of 4 weeks, baseline cholesterol synthesis will be measured (2H3 Leucine, 2H2O deuterated water). Then, treatment with rosuvastatin 10mg for 4 weeks will be initiated after which, patients will undergo glucose (2H2enriched glucose) and lipid flux (2H3 Leucine, 2H2O deuterated water and oral 1,2,3,4-13C16 - palmitate enrichment measurements) followed by 5 weeks treatment with dapagliflozin 10mg once daily. In the final week glucose/lipid flux measurements will be repeated.
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Sample Size: 12 DM2 subjects.
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Outcome measures: The primary endpoint is effect of 5 weeks Sodium-Glucose Linked co-transporter (SGLT) 2 inhibition on LDL cholesterol synthesis in patients with DM2. Secondary endpoints are effect of SGLT2 inhibition on triglyceride and cholesterol fluxes as well as (hepatic and peripheral) insulin sensitivity and energy expenditure. Finally, effect of SGLT2 inhibition on dietary intake, liver fat content (MRI liver) and fecal microbiome will be studied at these timepoints.